PRODUCT DETAILS

About Adefresh 400 Tablet

ADEMETIONINE belongs to the class of medication called Nutritional supplements primarily used to treat S-adenosylmethionine deficiency. Some patients with depression, Alzheimer's disease, dementia, Parkinson's disease treated with levodopa, disorders of folate metabolism, and other illnesses cause S-adenosylmethionine deficiency. ADEMETIONINE is a synthetic form of a chemical that occurs naturally in cells, tissue, and body fluids, primarily used to treat depression, reduce pain and swelling in the joints conditions such as osteoarthritis, biliary cholangitis (an autoimmune disease of the liver), excess cholesterol in bile and biliary and liver diseases caused by cystic fibrosis. It is also used to treat liver disease during pregnancy, improve symptoms in people with fibromyalgia, and treat nerve problems in people with AIDS or sexual dysfunction in men with depression.

ADEMETIONINE contains S-adenosylmethionine, a naturally occurring substance found in cells, tissue, and body fluids. It is produced from methionine (amino acid) and used to treat liver disease, depression, and osteoarthritis. ADEMETIONINE ensures sufficient levels of glutathione in the liver are maintained to minimize liver damage. It also prevents the increase of lipids associated with cirrhosis outside the liver. It also affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, regulating mood and treating depression. It stimulates the production of parts of cartilage, reduces the inflammatory mediator, and has painkilling properties.

Take ADEMETIONINE as prescribed by your doctor. You are advised to take ADEMETIONINE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal discomfort, abdominal pain, diarrhea, nausea, dizziness, insomnia. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not discontinue ADEMETIONINE without consulting your doctor. To treat your condition effectually, continue taking ADEMETIONINE for as long as prescribed. Do not take ADEMETIONINE if you are pregnant or breastfeeding unless prescribed. ADEMETIONINE can be given to children with extreme caution if prescribed by the doctor. Avoid consuming alcohol along with ADEMETIONINE as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of Adefresh 400 Tablet

Depression, Primary biliary cholangitis, Osteoarthritis

Medicinal Benefits of Adefresh 400 Tablet

The ADEMETIONINE contains S-adenosylmethionine, a naturally occurring substance in cells, tissue, and body fluids. It is produced from methionine (amino acid) and used to treat liver disease, depression, and osteoarthritis. In liver disease, ADEMETIONINE ensures sufficient glutathione levels in the liver to minimize liver damage. It also prevents the increase of lipids associated with cirrhosis outside the liver. In depression, it affects certain chemical messengers (serotonin) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. In osteoarthritis, It stimulates the production of cartilage parts, reduces the inflammatory mediator, and has painkilling properties. ADEMETIONINE is also effective in treating liver disease during pregnancy, improving symptoms in fibromyalgia, treating nerve problems in people with AIDS, or sexual dysfunction in men with depression.

Directions for Use

Oral tablet: Take ADEMETIONINE with food as prescribed by your doctor. The tablet form of ADEMETIONINE can be swallowed as a whole with a glass of water. Do not break, crush or chew it. Injection: The injection form of ADEMETIONINE will be administered by a healthcare professional. Do not self-administer.

Side Effects of Adefresh 400 Tablet

• Headache
• Dizziness
• Feeling anxious
• Vomiting
• Stomach upset
• Diarrhea
• Constipation
• Insomnia (sleep problem)
• Increased sweating

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Do not take ADEMETIONINE if you are allergic to any of its contents, if you have used an MAO inhibitor in the past 14 days, inflammation of gall bladder and bile ducts, narrowing or blockage bile ducts, biliary colic, calcified gallstones, improper constriction of the gallbladder, gastric or duodenal ulcer. Inform your doctor if you have heart disease, seizure disorders, bone marrow suppression, diabetes, schizophrenia, bipolar disorder, acute alcohol intoxication, glaucoma, thyroid problems, kidney and liver problems. Do not take ADEMETIONINE if you are pregnant or breastfeeding unless prescribed. ADEMETIONINE can be given to children with caution if prescribed by the doctor. Avoid consuming alcohol along with ADEMETIONINE as it could lead to increased drowsiness and liver damage. Keep your doctor informed about your health condition and medicines to rule out any unpleasant side effects. 

Drug Interactions

Drug-Drug Interaction:

ADEMETIONINE may have interaction with monoamine oxidase inhibitors (medicines used to treat depression) (moclobemide, phenelzine, iproniazid, isocarboxazid, nialamide, tranylcypromine, selegiline), an antidepressant (bupropion, duloxetine, fluoxetine, sertraline), antiparkinsons (levodopa), pain killers (tramadol, trazodone, hydrocodone, oxycodone, acetaminophen).

Drug-Disease Interaction:

ADEMETIONINE may have interactions with bipolar depression, Parkinson's disease, biliary obstruction and liver impairment, variceal bleeding (high blood pressure in portal veins), ascites (excess abdominal fluid), liver encephalopathy.

Safety Advice

ALCOHOL

Avoid consumption of alcohol while taking ADEMETIONINE as it may cause increased dizziness and liver damage.

PREGNANCY

Avoid taking ADEMETIONINE if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

BREAST FEEDING

Consult your doctor before taking ADEMETIONINE, your doctor will decide whether ADEMETIONINE can be taken by breastfeeding mothers or not.

DRIVING

ADEMETIONINE does not affect your ability to drive. However, you are advised to be cautious while driving if you experience dizziness.

LIVER

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

KIDNEY

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.